MHC Class I Synthesis

An Awe-Inspiring Window into aKey Process in Adaptive Immunity

Audra’s latest ‘bioscape’ features the synthesis and transport of MHC Class I molecules, key players in adaptive immunity.

The story depicted here has been simplified to provide a basic understanding of an important process in human immunity.

Golgi vesicles containing the MHC Class I molecules complexed to antigen shown leaving the Golgi apparatus

8 -10 amino acid long peptides (antigens) derived from a tumor or virus-infected cells

As always in medicine, the deeper you look, the more and more complex and awe-inspiring it becomes. The micro-verse is truly as infinite as the macro-verse, and the biggest challenge Audra faces as a biomedical artist is always the editing. Where to stop?!!